PDRunning backs are the lifeblood of any succe sful fantasy football team, and chances are, if you're in your semifinals, you have at least two good ones. Unfortunately, a few of those backs, including Kenneth Walker III, AJ Dillon, Alexander Mattison, and D'Onta Foreman, could be affected by injuries in Week 16, creating a domino effect that enhances or limits the value of other RBs.Below, we'll give you the latest news on these key RBs and break down how their injuries could potentially affect the Week 16 fantasy landscape.We'll continue to provide updates here right up until kickoff on Sunday, so check back for the latest.WEEK 16 INJURY UPDATES: | | Ronald Acuna Jr. Jersey UPDATE:ESPN's Adam Schefter reported late Saturday night that Walker is against the Titans.UPDATE 2:Walker is officially ACTIVE.Walker III (shoulder) after mi sing Wednesday's and Julio Teheran Jersey Thursday's se sions, but coach Pete Carroll a suaged everyone's fears by saying on Friday that Walker is "" against Tenne see.We'll take Carroll at his word and a sume Walker will be out there. As long as he is, he's a safe RB2 after his monster Week 15 against a nasty Eagles' run defense. Still, Walker owners would be wise to have a backup plan ready, with Seahawks' RB Zach Charbonnet being the obvious pivot if Walker mi ses time.WEEK 16 PPR RANKINGS | | | | | UPDATE:NFL Network's Tom Peli sero reported late Saturday night that Mattison is against the Lions.UPDATE 2:Mattison is officially ACTIVE.Mattison (ankle) after starting the week with two DNPs. He appears to be a true game-time decision for Minnesota's game against Detroit.Ultimately, Mattison doesn't have much standalone value at this point anyway. Earlier this week, Vikings' coach Kevin O'Connell implied that Ty Chandler even when Mattison returns, so Mattison's presence would mainly serve as a nuisance for Chandler owners. Against Detroit's No. 1 RB defense and Sean Newcomb Jersey eighth-ranked run defense, Chandler would be a mid-tier flex if Mattison is back. If Mattison remains out, Chandler bumps up to a low-end RB2/high-end flex.WEEK 16 STANDARD RANKINGS | | | | | UPDATE:Dillon is officially ACTIVE.Dillon (broken thumb) after mi sing last week's game. It seems likely he'll return from his brief hiatus and split carries with Aaron Jones against the Panthers, but given the nature of his injury, it's po sible he sits out another contest.Either way, it's tough to trust Dillon despite the premium matchup. He failed to do much even when Jones was out, so it's tough to imagine him getting enough touches to provide flex value with Jones back. He could always score a short TD, but we wouldn't bank on that. Jones is a must-start Mark Melancon Jersey either way given the matchup against a Carolina defense allowing the third-most fantasy points to RBs, but his value would would rise if Dillon is out.WEEK 16 DFS: | | | UPDATE:NFL Network's Ian Rapoport reported Sunday morning that Foreman is against the Cardinals.UPDATE 2:Foreman is officially OUT.Foreman (personal) mi sed practice on Thursday, but he on Friday. Still, the Bears listed him as "questionable" ahead of a cake matchup against Arizona.WEEK 16 FANTASY ADVICE: | | | Foreman started last week, but after totaling -6 yards on six carries, he was quickly shuttered to the sidelines in favor of Khalil Herbert (six carries, eight yards) and Roschon Johnson (five carries, 36 yards). That was against Cleveland's dominant run defense, though, and against Arizona's 31st-ranked unit, whoever gets carries for the Bears should have fantasy value. Unfortunately, that's impo sible Matt Joyce Jersey to predict right now, and Foreman's lack of practice time doesn't help him. There's a chance he has a good game, but only those in very deep leagues should take a chance on him. We slightly favor Johnson over Herbert.